Dean Flow-coupled Inertial Focusing for Ultra-high-throughput Particle Filtration

نویسندگان

  • S. Ardabili
  • J. Gantelius
  • J. Kowalewski
  • H. Brismar
  • A. Russom
چکیده

Particle manipulation represents an important and fundamental step prior to counting, sorting and detecting bioparticles. In this study, we report dean-coupled inertial focusing of particles in flows through a single curve microchannel at extremely high channel Reynold numbers (~325). We found the lateral particle focusing position, xf to be fixed and largely independent of radius of curvature and whether particles are pre-focused (at equilibrium) entering the curvature or randomly distributed. Finally, using a single inlet, u-shaped, microchannel we demonstrate filtration of 10μm particles from 2 μm particles at throughputs several orders of magnitude higher than previously shown.

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تاریخ انتشار 2010